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Certain Medical Conditions Individuals with certain medical conditions, such as pernicious anemia, may experience B12 deficiency as their body cannot produce enough intrinsic factors, a protein necessary for B12 absorption

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According to the NIH Office of Dietary Supplements, B12 plays a key role in: Making red blood cells and preventing megaloblastic anemia Maintaining healthy nerve function and the myelin sheath that protects nerves DNA synthesis Supporting brain function and preventing cognitive decline Converting food into energy (cellular metabolism) Because B12 is found almost exclusively in animal products meat, fish, dairy, and eggs certain groups of people are at much higher risk of deficiency than others

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